TFC  /  Compounding  /  What Is Compounding?
Compounding 101 · Patient education

A medication doesn't have to come from a factory.

Pharmacy compounding is the creation of a personalized medication, prepared by a pharmacist to a prescriber's exact specification. When a manufactured drug doesn't fit — the wrong dose, the wrong form, an allergy, a shortage, a discontinued medication — a compounding pharmacy can make what the patient actually needs.

Compounding workstation at TFC Pharmacy
Made
by hand
503A
Patient-specific compounding
PCAB
Specialty accreditation
USP <795>
Non-sterile standards
Custom
Dose · form · allergens
Why compound

Three reasons patients need a compounding pharmacy.

Many people aren't served by mass-produced medications. Here's how compounding fills the gap.

REASON 01

The right dose, in the right form.

Manufactured drugs come in standardized strengths and forms. We can prepare any dose your prescriber specifies — half of a tablet's strength, double, or anywhere in between — and in the form that works best for the patient: a liquid for a child, a cream for absorption through skin, a lozenge for the elderly.

REASON 02

Without the ingredients you can't tolerate.

Mass-produced drugs include dyes, fillers, gluten, lactose, and preservatives that some patients react to. We compound from the active pharmaceutical ingredient up, so we can leave out what doesn't agree with the patient and use bases compatible with allergies and sensitivities.

REASON 03

When the medication isn't made anymore.

Drugs get discontinued. Manufacturers leave the market. Shortages happen. For many of those medications, we can reproduce the formula from the active pharmaceutical ingredient — so the patient who relied on it for years doesn't have to switch to something that doesn't work as well.

Real situations

When compounding makes all the difference.

Every example below is the kind of prescription we fill weekly at TFC.

A child · age 4
Can't swallow a pill.

Pediatrician prescribed omeprazole for reflux, but the only tablet available is the wrong dose and too large to swallow.

→ Flavored oral suspension at correct mg/kg dose.
A woman · age 52
Allergic to a dye in the brand-name HRT.

Patient developed a rash from the commercial estradiol patch within a week. Doctor switched her to compounded therapy.

→ Bioidentical estradiol cream, dye-free base.
A retired man · age 71
His Parkinson's medication is off the market.

The brand his neurologist prescribed for 12 years was discontinued. The replacements don't control his tremor as well.

→ Capsule compounded from the active ingredient.
A cat · age 9
Won't swallow the thyroid pill.

Hyperthyroid cat needs methimazole twice daily. Owner can't pill her. Vet asked for a transdermal preparation.

→ PLO gel applied to the inside of the ear.
Dosage forms we prepare

Twelve different ways to take a medication.

If the manufactured form isn't working, there's almost always another way to deliver the same active ingredient. Here's our working repertoire.

Capsules

Custom-strength capsules in any milligram dose. Vegetarian, dye-free, gluten-free, and slow-release shells available.

Oral

Oral suspensions

Liquid medication, dose-titratable by the milliliter. Flavored bubblegum, cherry, grape, or unflavored. Dye- and sugar-free options.

Oral

Troches & lozenges

Dissolve under the tongue or on the cheek. Useful when GI absorption is poor or for hormones that bypass the liver.

Sublingual

Topical creams

Anhydrous, Lipoderm, HRT-Heaven, and PLO bases for transdermal absorption. Common for HRT, pain compounds, and pediatric medications.

Topical

Gels & ointments

For topical pain compounds, hormone therapies, dermatology preparations, and vaginal applications.

Topical

Suppositories

Rectal or vaginal delivery for patients who can't take medication orally — nausea, post-surgical, or for localized treatment.

Rectal / Vaginal

Lollipops & chewables

For children who won't take medication any other way, or for cats and dogs. Flavored to mask bitter actives.

Pediatric / Vet

Sterile injectables

Prepared in our USP <797> cleanroom. Hormones, peptides, vitamin infusions, and other parenteral preparations.

Injectable · USP 797

Nasal sprays

For sinus, anti-inflammatory, allergy, and migraine therapies. Compounded with preservative-free vehicles for sensitive patients.

Intranasal

Mouthwashes & rinses

"Magic mouthwash" combinations for chemotherapy mucositis, dental procedures, and oral pain — compounded to prescriber specification.

Oral rinse

Eye & ear drops

Sterile preparations for ophthalmic and otic use. Useful for preservative-sensitive patients and discontinued formulations.

Ophthalmic · Otic

Veterinary chews

Chicken-, tuna-, or peanut butter-flavored soft chews for dogs and cats. Custom strengths and combinations.

Veterinary
Standards & safety

Compounded under three U.S. Pharmacopeia chapters.

USP — the United States Pharmacopeia — sets the legal standards for how compounded medications are prepared, tested, and dispensed. TFC is compliant with all three.

USP <795> ✓ Compliant

Non-sterile compounding.

The standard for non-sterile preparations — creams, capsules, oral suspensions, troches, gels.

  • Documented standard operating procedures
  • Beyond-use dating per stability data
  • Annual environmental monitoring
  • Inspected biennially by CA Board of Pharmacy
USP <797> ✓ Compliant

Sterile compounding.

The standard for sterile preparations — injectables, IV admixtures, ophthalmic drops.

  • ISO Class 5 laminar airflow workbench
  • ISO Class 7 buffer room, ISO Class 8 ante-room
  • Monthly viable and non-viable air sampling
  • Annual personnel media-fill testing
USP <800> ✓ Compliant

Hazardous drugs.

The standard for handling NIOSH-listed hazardous drugs — chemotherapy adjuvants, certain hormones, antivirals.

  • Negative-pressure containment room
  • Closed-system transfer devices
  • Annual surface wipe testing for residue
  • Dedicated PPE & staff training
Compounding glossary

The vocabulary, plainly.

Terms you'll hear from us or your prescriber when a compound is being prepared.

API acronym
Active Pharmaceutical Ingredient. The chemical that actually does the work in a medication — what we measure, weigh, and combine with a base to make the final preparation.
BUD acronym
Beyond-Use Date. The date after which a compounded preparation should not be used. Assigned per USP guidelines and, for complex formulas, third-party stability data.
Base / vehicle
The inactive carrier that delivers the API. For a cream, the base might be Lipoderm or HRT-Heaven; for a suspension, it might be Ora-Sweet or an alcohol-free SyrSpend SF.
Anhydrous
Containing no water. Anhydrous bases are used for preparations that would be unstable in the presence of water — most notably certain hormones and some antibiotics.
PLO gel
Pluronic Lecithin Organogel. A transdermal delivery vehicle that helps medications cross the skin barrier. Common for pain compounds, anti-emetics, and veterinary transdermals.
Troche
A medicated lozenge that dissolves in the mouth. Useful for medications absorbed through the oral mucosa or for patients who can't swallow pills.
Mold
A reusable form into which a compound is poured to set — for suppositories, troches, lollipops, and gummies. Different molds shape and size the final preparation.
BHRT acronym
Bioidentical Hormone Replacement Therapy. Hormones with the same molecular structure as the body's own, compounded to a prescriber's dose for individual patients.
BCSCP acronym
Board-Certified Sterile Compounding Pharmacist. An advanced credential for pharmacists specializing in USP <797> sterile preparations. Two of our pharmacists hold it.
Memberships & accreditation

The standards we work to are not optional.

PCCA

Member since 2003

Professional Compounding Centers of America. Access to 8,000+ peer-reviewed formulas, bases, and compounding technology.

PCAB

Accredited compounding pharmacy

The Pharmacy Compounding Accreditation Board. Triennial audits of our facility, procedures, and recordkeeping.

CA Board

California State Board of Pharmacy

California State Board of Pharmacy. Biennial inspection; sterile compounding license endorsement on file.

ACA

Member · American College of Apothecaries

National professional association for compounding pharmacists. Continuing education, advocacy, and standards.

Have a prescription?

Bring it to us. We'll take it from here.

Turnaround depends on dosage form and complexity. We'll confirm timing and notify you when your order is ready.